I recently read your article regarding methylation and it is brilliant. I had anxiety and panic attacks that never responded to any medications and took Deplin (a form of Vitamin B9) and it was like a miracle, the anxiety was gone. Now I am taking Deplin and have been off Klonopin for 6 months after 25 years. I am suffering from benzo withdrawal but it is quite mild but, I feel I am close to being cured. I also take manganese and it works magically at stopping the anxiety.